Sun-Drenched Mediterranean Pork Tenderloin

Flavorful Mediterranean Baked Pork Tenderloin: A Healthy & Easy Weeknight Recipe

Embark on a culinary journey to the sun-drenched coasts of the Mediterranean with this exquisite Mediterranean Baked Pork Tenderloin recipe. This dish promises a tender, juicy, and incredibly flavorful experience, infused with a harmonious blend of warm, aromatic spices. Perfect for a busy weeknight yet impressive enough for guests, this recipe elevates simple pork tenderloin into a memorable meal that the whole family will adore. Prepare to transform your dinner table with the vibrant tastes of the Mediterranean!

Tender and juicy Mediterranean Baked Pork Tenderloin, seasoned with a warm Mediterranean spice blend, baked to perfection for an easy weeknight family meal.

Get ready for a truly delightful culinary experience! If you appreciate the rich taste and versatility of pork, this Mediterranean Baked Pork Tenderloin recipe is an absolute must-try. It combines the lean, succulent qualities of pork tenderloin with the aromatic spices that define Mediterranean cuisine, resulting in a dish that’s both healthy and bursting with flavor. Forget bland dinners; this recipe is about to become a new favorite in your cooking repertoire.

Why Choose Pork Tenderloin?

Pork tenderloin is often celebrated as one of the easiest and healthiest cuts of pork to cook, making it an ideal choice for quick weeknight meals. It’s a remarkably lean cut, comparable to chicken breast in its nutritional profile, providing an excellent source of high-quality protein without excessive fat. Its mild flavor acts as a perfect canvas for a wide array of seasonings, especially the robust Mediterranean spice mixture we use in this recipe.

Many home cooks might shy away from baking pork tenderloin, but it’s one of the most foolproof methods to achieve a tender and juicy result. Unlike pork chops, which can dry out quickly, tenderloin retains its moisture wonderfully when cooked to the correct internal temperature. There’s a common misconception that pork needs to be cooked until it’s completely white or gray to be safe. However, according to USDA guidelines, pork is perfectly safe and most delicious when cooked to an internal temperature of 145°F (63°C), which often leaves a slight “blush of pink” in the center. This slight pink hue is actually a sign of a perfectly cooked, succulent piece of meat, ensuring it’s never dry or tough.

The beauty of baked pork tenderloin also lies in its adaptability. You can enjoy it as is, allowing the Mediterranean spices to shine, or pair it with an array of sauces, from a tangy BBQ glaze to a fresh herb chimichurri. For those who love exploring pork recipes, be sure to check out my full collection of pork recipes here. You might also enjoy other favorites like my Pineapple Pork Chops, BBQ Baked Pork Chops, Cast Iron Pork Tenderloin, Air Fryer Pork Tenderloin, or these delightful Pan Seared Pork Chops.

Essential Ingredients for Your Pork Tenderloin

Close-up of raw pork tenderloin with Mediterranean spices and fresh garlic, ready for baking.

Crafting the perfect Mediterranean Baked Pork Tenderloin starts with high-quality ingredients and a carefully balanced spice blend. Below, you’ll find a detailed look at the key components of this recipe. For precise measurements and step-by-step instructions, please refer to the complete recipe card provided further down.

  • Pork Tenderloin: This recipe calls for either two small pork tenderloins or one large one, totaling approximately two pounds. Pork tenderloin is a long, narrow, and lean cut of meat from the loin of the pig. It’s crucial to prepare it by trimming the “silver skin”—a thin, silvery membrane that, if left on, can make the cooked pork tough and chewy. Removing it ensures a tender texture.
  • Mediterranean Spice Rub: The heart of this dish’s flavor lies in its rich and aromatic spice blend. This warm mixture deeply infuses the pork with the distinctive tastes of the Mediterranean. It includes:
    • Coriander: Offers a sweet, floral, and slightly citrusy note.
    • Cumin: Provides an earthy, warm, and slightly pungent flavor that is central to many Mediterranean dishes.
    • Cinnamon: Adds a touch of sweet warmth and complexity, balancing the savory spices.
    • Allspice: Delivers a hint of cloves, nutmeg, and cinnamon, creating a unified warm aroma.
    • Cloves: Contributes a strong, sweet, and pungent aroma, used sparingly for depth.
    • Oregano: A classic Mediterranean herb, offering a robust, earthy, and slightly peppery flavor.
    • Cayenne Red Pepper: (Optional) A pinch of cayenne adds a subtle kick, enhancing the warmth without overwhelming the palate.

    This combination creates a beautifully fragrant crust on the pork, sealing in juices and layering flavor.

  • Garlic: Fresh garlic is indispensable in Mediterranean cooking, providing a pungent, aromatic base that complements the spices beautifully. We’ll be inserting small pieces of chopped garlic directly into the tenderloin, ensuring every bite is permeated with its delicious essence. If fresh garlic isn’t available, or you prefer a quicker alternative, you can substitute it with garlic powder, adding it directly to your spice rub mixture.

Creative Ways to Modify Your Mediterranean Pork Tenderloin

This Mediterranean Baked Pork Tenderloin recipe is wonderfully versatile, allowing for numerous modifications to suit your taste preferences or what you have on hand. Don’t hesitate to experiment and make it your own! Here are some fantastic ideas to get you started:

  • Brighten with Lemon: A squeeze of fresh lemon juice or a sprinkle of lemon zest can dramatically brighten the flavors of the pork. The acidity from the lemon not only adds a delightful citrusy tang but also acts as a natural tenderizer, helping to break down muscle fibers and create an even juicier pork tenderloin. You can add it before baking as part of a marinade or drizzle it over the cooked pork just before serving.
  • Add Feta Cheese: For an extra layer of salty, tangy goodness, consider crumbling some feta cheese over the pork during the last 5-10 minutes of baking, or sprinkle it on after slicing. The creamy, briny notes of feta pair exceptionally well with the rich spices and tender pork, adding a quintessential Mediterranean touch.
  • Marinate with Vinegar: To infuse deeper flavor and tenderize the pork even further, consider marinating it for at least 30 minutes (or up to a few hours) with a splash of vinegar. Balsamic vinegar offers a sweet and tangy depth, red wine vinegar provides a sharp, fruity note, and white wine vinegar lends a crisp, clean acidity. Combine your chosen vinegar with the spices and a drizzle of olive oil for an effective marinade.
  • Explore More Spices: While our core spice rub is fantastic, feel free to enhance it with other complementary spices. Paprika (sweet or smoked) can add color and a mild pepperiness, thyme offers an earthy, slightly minty note, onion powder provides savory depth, chili powder can increase the heat, and Italian seasoning can bring a familiar aromatic blend. Adjust quantities to taste.
  • Fresh Herbs for a Finishing Touch: Fresh herbs are a Mediterranean staple and can truly elevate the dish. After baking, finely chop fresh parsley, oregano, or thyme and sprinkle generously over the sliced pork. The fresh, vibrant flavors and aromas provide a beautiful contrast to the warm, cooked spices and add a pop of color.
  • Incorporate Vegetables for a One-Pan Meal: For a complete meal cooked in one pan, chop hearty vegetables like bell peppers (red, yellow, orange), zucchini, cherry tomatoes, red onion, or even small potatoes. Toss them with a little olive oil, salt, pepper, and some of the Mediterranean spice mix, then arrange them around the pork tenderloin in the baking dish. They’ll roast alongside the pork, absorbing its flavors and creating a convenient and healthy side.
Hands rubbing Mediterranean spice mixture onto pork tenderloin on a cutting board, preparing it for baking.

How to Make This Flavorful Baked Pork Tenderloin Recipe

Creating this delicious Mediterranean Baked Pork Tenderloin is surprisingly simple, making it perfect for both novice and experienced cooks. Follow these straightforward steps to achieve a perfectly seasoned and juicy result every time:

First, preheat your oven to 375 degrees F (190°C). Ensuring your oven is at the correct temperature before placing the pork in is crucial for even cooking and achieving that desirable crust.

Step 1: Prepare the Mediterranean Spice Rub: In a small bowl, combine all the dry spices: coriander, cumin, cinnamon, allspice, cloves, oregano, and cayenne pepper (if using). Stir them thoroughly until they are well integrated. This ensures that each spoonful of rub offers a balanced flavor profile. Set this fragrant mixture aside; it’s the secret to our Mediterranean magic!

Step 2: Trim the Pork Tenderloin and Infuse with Garlic: Place your pork tenderloin on a clean, large cutting board. The first important step is to trim any “silver skin” – a thin, silvery membrane that runs along one side of the tenderloin. This membrane doesn’t render during cooking and can make the pork tough. To remove it, slide a sharp knife just under the silver skin at one end, lift it slightly, and carefully slice it away from the meat, angling the knife slightly upwards. Once trimmed, use a sharp knife to cut three small slits into each pork tenderloin, about an inch deep. Carefully insert a small piece of chopped garlic into each slit, pushing it firmly into the meat to ensure the garlic is nestled securely inside. This technique allows the garlic flavor to penetrate deep into the pork as it bakes.

Step 3: Season the Pork with the Spice Rub: Generously using your hands (or a spoon), rub the prepared Mediterranean spice mixture all over each pork tenderloin, ensuring both sides and ends are thoroughly coated. Gently massage the spices into the meat to help them adhere and infuse flavor. After applying the spice rub, lightly sprinkle all sides of the pork with salt and freshly ground black pepper to taste. Don’t be shy with the seasoning; it’s what creates that irresistible flavor.

Step 4: Roast to Perfection: Carefully transfer the seasoned pork tenderloin to a large baking dish or a rimmed baking sheet. Ensure there’s enough space around the tenderloins for even air circulation. Bake the tenderloin in your preheated oven at 375 degrees F for approximately 30-35 minutes. The most accurate way to determine doneness is by using an instant-read meat thermometer. Insert the thermometer into the thickest part of the pork, avoiding any bone if present. The internal temperature should register 145 degrees F (63°C). At this temperature, the pork will be incredibly juicy and tender, with a beautiful “blush of pink” still visible in the center, and a delicious spiced crust on the outside. This blush of pink is a sign of perfectly cooked pork, not undercooked!

Sliced Mediterranean Baked Pork Tenderloin garnished with fresh parsley on a white platter, ready to serve.

Once baked, remove the pork tenderloin from the oven and transfer it to a cutting board. It’s crucial to let the meat rest for 5-10 minutes before slicing. This resting period allows the juices to redistribute throughout the meat, resulting in a more tender and flavorful final product. If you slice it too soon, the juices will simply run out, leaving you with drier pork. After resting, slice the pork tenderloin into thin, even cuts against the grain, and serve immediately. A sprinkle of fresh parsley as a garnish adds a burst of color and a touch of fresh herbaceousness, enhancing both the visual appeal and the flavor.

Storing Leftovers

If you happen to have any delicious leftovers, store them properly to enjoy later. Place the sliced pork tenderloin in an airtight container and refrigerate for up to 3-4 days. For best results when reheating, gently warm the pork in a preheated oven at a lower temperature (around 300°F/150°C) until just heated through, or briefly pan-fry it to prevent it from drying out. A quick microwave reheat is also an option, though it might slightly alter the texture.

Close-up of a fork lifting a piece of perfectly cooked Mediterranean Baked Pork Tenderloin, showcasing its tender texture.

Perfect Pairings: What to Serve with Mediterranean Baked Pork Tenderloin

The beauty of this Mediterranean Baked Pork Tenderloin is its versatility, allowing it to be paired with a wide range of complementary side dishes. To complete your meal, consider these fresh, vibrant, and hearty options that echo the flavors of the Mediterranean:

Fresh Salads

Light and crisp salads are an excellent contrast to the rich, spiced pork. They add a refreshing element and can be easily prepared while the pork bakes.

  • Lemon Arugula Salad Recipe with Parmesan Cheese: The peppery bite of arugula, bright lemon dressing, and salty Parmesan offer a fantastic flavor contrast.
  • Fattoush Salad: A classic Lebanese bread salad with mixed greens, vegetables, and toasted pita, dressed in a zesty sumac vinaigrette, is perfect for a full Mediterranean experience.
  • Greek Quinoa Salad: Packed with protein from quinoa, fresh vegetables, olives, and feta cheese, this salad adds substance and a medley of textures and flavors.
  • Easy Lebanese Salad: A simple yet flavorful salad typically featuring finely chopped tomatoes, cucumbers, and parsley, dressed with lemon and olive oil, provides a refreshing balance.

Roasted Vegetables

Roasting vegetables alongside or separately from the pork is a convenient way to add nutrients and complementary flavors. They caramelize beautifully, bringing out their natural sweetness.

  • Bok Choy: Sautéed or lightly roasted bok choy can offer a tender, slightly sweet green side that’s quick to prepare.
  • Simple Garlic Parmesan Green Beans: Crispy green beans tossed with garlic and Parmesan are a crowd-pleaser and offer a delicious savory crunch.
  • Mediterranean Roasted Vegetables: A medley of bell peppers, zucchini, red onion, and cherry tomatoes roasted with olive oil and herbs creates a vibrant and flavorful accompaniment that perfectly aligns with the dish’s theme.

Hearty Grains & Potatoes

For a more filling meal, consider pairing the tenderloin with a side of grains or potatoes, which can soak up the delicious pan juices and spices.

  • Lemon Cilantro Roasted Potatoes: Roasted potatoes infused with lemon and cilantro provide a tangy and aromatic starch component.
  • Lebanese Spicy Potatoes (Batata Harra): If you enjoy a bit of heat, these cubed and fried potatoes seasoned with chili, garlic, and cilantro are an exciting and flavorful choice.
  • Lemon Pearl Couscous Recipes: Light and fluffy pearl couscous, brightened with lemon, makes an excellent, quick-cooking side that absorbs flavors wonderfully.
  • Cauliflower Potato Salad: A lighter take on traditional potato salad, offering creamy texture with fewer carbs but plenty of flavor.

Explore More Delicious Pork Recipes

If you’re a fan of pork and always looking for new ways to prepare this versatile meat, here are some other fantastic recipes to inspire your next meal. From smoky grilled chops to savory stir-fries, there’s a pork dish for every occasion.

Pork

Grilled Hawaiian Pork Chops

Pork

Easy Thai Pork Stir-Fry

Mediterranean

Pork Souvlaki with Tzatziki

Pork

Pork Burgers

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4.50 from 2 votes

Mediterranean Baked Pork Tenderloin

By Julia Jolliff
This Mediterranean Baked Pork Tenderloin is an incredibly tender and juicy dish, bursting with the authentic flavors of the Mediterranean. Rubbed with a warm, aromatic spice blend and baked to perfection, it’s an easy, healthy, and satisfying meal that your entire family will absolutely love. Ideal for a quick weeknight dinner or a special gathering!
Mediterranean Baked Pork Tenderloin 1200 x 1200
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Prep: 15 minutes
Cook: 30 minutes
Total: 45 minutes
Servings: 6

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Ingredients 

  • 2 small pork tenderloins or 1 large pork tenderloin {about 2 pounds of pork tenderloin}
  • 1 garlic clove, chopped into 6 small pieces
  • Salt
  • Pepper

Mediterranean Spice Mix:

  • 1 teaspoon coriander
  • 1 teaspoon cumin
  • 1 teaspoon cinnamon
  • 1/2 teaspoon allspice
  • 1/4 teaspoon cloves
  • 1 teaspoon oregano
  • 1/4 teaspoon cayenne red pepper {optional for spice}

Garnish:

  • Fresh Parsley

Instructions 

  • Preheat oven to 375 degrees F (190°C).
  • In a small bowl, combine the coriander, cumin, cinnamon, allspice, cloves, oregano, and cayenne pepper. Stir well until all spices are thoroughly mixed. Set aside.
  • Place the pork tenderloin on a large cutting board. Carefully trim any “silver skin” from the pork by sliding a sharp knife just under it and slicing it away.
  • Cut 3 small slits into each pork tenderloin using a sharp knife. Insert a small piece of chopped garlic into each slit, pushing it firmly into the meat.
  • Using your hands, rub the Mediterranean spice mixture generously over both sides of each pork tenderloin. Lightly sprinkle all sides with salt and pepper.
  • Place the seasoned pork tenderloin in a large baking dish or on a rimmed baking sheet. Bake at 375 degrees F for 30-35 minutes, or until an instant-read meat thermometer inserted into the thickest part of the pork registers an internal temperature of 145 degrees F (63°C). The pork should have a beautiful blush of pink in the center, which indicates it’s perfectly cooked and juicy, along with a nice spiced crust. Remove from the oven and allow to rest on a cutting board for 5-10 minutes. Slice the pork tenderloin into thin cuts against the grain and serve immediately, garnished with fresh parsley.

Notes

  • The presence of a “blush of pink” in the pork is not only safe (at 145°F/63°C internal temperature) but also a sign of perfectly cooked, tender, and juicy pork! Overcooking will lead to dry, tough meat. Always use a reliable meat thermometer.
  • For an extra layer of subtle aroma, you can also cut small pieces of bay leaves and tuck them into the pork alongside the garlic. Make a few small slits in the pork and insert the bay leaf pieces. Remember to remove them before serving, as bay leaves are not meant to be eaten.
  • For easy cleanup, line your baking dish or sheet with parchment paper or foil before baking.
  • Consider briefly searing the pork tenderloin in a hot, oven-safe skillet for 2-3 minutes per side before transferring it to the oven. This can help create an even better crust and lock in more juices, adding an extra dimension of flavor and texture.

Nutrition

Calories: 731kcal, Carbohydrates: 1g, Protein: 125g, Fat: 22g, Saturated Fat: 7g, Polyunsaturated Fat: 3g, Monounsaturated Fat: 8g, Trans Fat: 0.2g, Cholesterol: 393mg, Sodium: 316mg, Potassium: 2398mg, Fiber: 1g, Sugar: 0.04g, Vitamin A: 59IU, Vitamin C: 0.4mg, Calcium: 53mg, Iron: 6mg

Nutrition information is automatically calculated, so should only be used as an approximation.

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